Principles of early human development and germ cell program from conserved model systems
Human primordial germ cells (hPGCs), the precursors of sperm and eggs, originate during week 2-3 of early postimplantation development(1). Using in vitro models of hPGC induction(2-4), recent studies suggest striking mechanistic differences in specification of human and mouse PGCs(5). This may partl...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Published: |
Nature Publishing Group
2017
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| Online Access: | https://eprints.nottingham.ac.uk/43643/ |