High-throughput spheroid screens using volume, resazurin reduction and acid phosphatase activity

Mainstream adoption of physiologically-relevant three-dimensional models has been slow in the last 50 years due to long, manual protocols with poor reproducibility, high price and closed commercial platforms. This chapter describes high-throughput, low-cost, open methods for spheroid viability asses...

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Bibliographic Details
Main Authors: Ivanov, Delyan Pavlov, Grabowska, Anna M., Garnett, Martin C.
Other Authors: Gilbert, Daniel F.
Format: Book Section
Published: Humana Press (Springer) 2017
Subjects:
Online Access:https://eprints.nottingham.ac.uk/43565/