Enantioselective copper-catalyzed reductive coupling of vinylazaarenes with N-Boc aldimines
The diastereo- and enantioselective reductive coupling of vinylazaarenes with N-Boc aldimines is described. The reactions proceed using chiral copper–bisphosphine complexes in the presence of TMDS as a hydride source to give reductive coupling products in moderate to high enantioselectivities.
| Main Authors: | , , , , |
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| Format: | Article |
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Thieme
2015
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| Online Access: | https://eprints.nottingham.ac.uk/43480/ |
| _version_ | 1848796698019627008 |
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| author | Choi, Bonnie Saxena, Aakarsh Smith, Joshua J. Churchill, Gwydion H. Lam, Hon Wai |
| author_facet | Choi, Bonnie Saxena, Aakarsh Smith, Joshua J. Churchill, Gwydion H. Lam, Hon Wai |
| author_sort | Choi, Bonnie |
| building | Nottingham Research Data Repository |
| collection | Online Access |
| description | The diastereo- and enantioselective reductive coupling of vinylazaarenes with N-Boc aldimines is described. The reactions proceed using chiral copper–bisphosphine complexes in the presence of TMDS as a hydride source to give reductive coupling products in moderate to high enantioselectivities. |
| first_indexed | 2025-11-14T19:52:07Z |
| format | Article |
| id | nottingham-43480 |
| institution | University of Nottingham Malaysia Campus |
| institution_category | Local University |
| last_indexed | 2025-11-14T19:52:07Z |
| publishDate | 2015 |
| publisher | Thieme |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | nottingham-434802020-05-04T17:01:51Z https://eprints.nottingham.ac.uk/43480/ Enantioselective copper-catalyzed reductive coupling of vinylazaarenes with N-Boc aldimines Choi, Bonnie Saxena, Aakarsh Smith, Joshua J. Churchill, Gwydion H. Lam, Hon Wai The diastereo- and enantioselective reductive coupling of vinylazaarenes with N-Boc aldimines is described. The reactions proceed using chiral copper–bisphosphine complexes in the presence of TMDS as a hydride source to give reductive coupling products in moderate to high enantioselectivities. Thieme 2015-02-28 Article PeerReviewed Choi, Bonnie, Saxena, Aakarsh, Smith, Joshua J., Churchill, Gwydion H. and Lam, Hon Wai (2015) Enantioselective copper-catalyzed reductive coupling of vinylazaarenes with N-Boc aldimines. Synlett, 26 (3). pp. 350-351. ISSN 1437-2096 Asymmetric catalysis Copper Enantioselectivity Imines Vinylazaarenes https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0034-1379548 doi:10.1055/s-0034-1379548 doi:10.1055/s-0034-1379548 |
| spellingShingle | Asymmetric catalysis Copper Enantioselectivity Imines Vinylazaarenes Choi, Bonnie Saxena, Aakarsh Smith, Joshua J. Churchill, Gwydion H. Lam, Hon Wai Enantioselective copper-catalyzed reductive coupling of vinylazaarenes with N-Boc aldimines |
| title | Enantioselective copper-catalyzed reductive coupling of vinylazaarenes with N-Boc aldimines |
| title_full | Enantioselective copper-catalyzed reductive coupling of vinylazaarenes with N-Boc aldimines |
| title_fullStr | Enantioselective copper-catalyzed reductive coupling of vinylazaarenes with N-Boc aldimines |
| title_full_unstemmed | Enantioselective copper-catalyzed reductive coupling of vinylazaarenes with N-Boc aldimines |
| title_short | Enantioselective copper-catalyzed reductive coupling of vinylazaarenes with N-Boc aldimines |
| title_sort | enantioselective copper-catalyzed reductive coupling of vinylazaarenes with n-boc aldimines |
| topic | Asymmetric catalysis Copper Enantioselectivity Imines Vinylazaarenes |
| url | https://eprints.nottingham.ac.uk/43480/ https://eprints.nottingham.ac.uk/43480/ https://eprints.nottingham.ac.uk/43480/ |