Defining the ABC of gene essentiality in streptococci

Background: Utilising next generation sequencing to interrogate saturated bacterial mutant libraries provides unprecedented information for the assignment of genome-wide gene essentiality. Exposure of saturated mutant libraries to specific conditions and subsequent sequencing can be exploited to unc...

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Bibliographic Details
Main Authors: Charbonneau, Amelia R. L., Forman, Oliver P., Cain, Amy K., Newland, Graham, Robinson, Carl, Boursnell, Mike, Parkhill, Julian, Leigh, James A., Maskell, Duncan J., Waller, Andrew S.
Format: Article
Published: BioMed Central 2017
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Online Access:https://eprints.nottingham.ac.uk/43394/