Therapeutic concentrations of antidepressants inhibit pancreatic beta-cell function via mitochondrial complex inhibition
Diabetes mellitus risk is increased by prolonged usage of antidepressants (ADs). Although various mechanisms are suggested for their diabetogenic potential, whether a direct effect of ADs on pancreatic β-cells is involved is unclear. We examined this idea for 3 ADs: paroxetine, clomipramine and, wit...
| Main Authors: | , , , , , |
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| Format: | Article |
| Published: |
Oxford University Press
2017
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| Subjects: | |
| Online Access: | https://eprints.nottingham.ac.uk/43309/ |