RECQ1 expression is upregulated in response to DNA damage and in a p53-dependent manner

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RECQ1 expression is upregulated in response to DNA damage and in a p53-dependent manner

Sensitivity of cancer cells to DNA damaging chemotherapeutics is determined by DNA repair processes. Consequently, cancer cells may upregulate the expression of certain DNA repair genes as a mechanism to promote chemoresistance. Here, we report that RECQ1, a breast cancer susceptibility gene that...

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Bibliographic Details
Main Authors:	Parvathaneni, Swetha, Lu, Xing, Choudhary, Ritu, Lal, Ashish, Madhusudan, Srinivasan, Sharma, Sudha
Format:	Article
Published:	Impact Journals 2017
Subjects:	RecQ Helicase DNA damage p53 Gene expression
Online Access:	https://eprints.nottingham.ac.uk/43227/

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