RECQ1 expression is upregulated in response to DNA damage and in a p53-dependent manner
Sensitivity of cancer cells to DNA damaging chemotherapeutics is determined by DNA repair processes. Consequently, cancer cells may upregulate the expression of certain DNA repair genes as a mechanism to promote chemoresistance. Here, we report that RECQ1, a breast cancer susceptibility gene that...
| Main Authors: | , , , , , |
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| Format: | Article |
| Published: |
Impact Journals
2017
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| Subjects: | |
| Online Access: | https://eprints.nottingham.ac.uk/43227/ |