VEGF-A165b protects against proteinuria in a mouse model with progressive depletion of all endogenous VEGF-A splice isoforms from the kidney

VEGF-A165b protects against proteinuria in a mouse model with progressive depletion of all endogenous VEGF-A splice isoforms from the kidney

Chronic kidney disease (CKD) is strongly associated with a decrease in the expression of VEGF-A. However, little is known about the contribution of VEGF-A splice isoforms to kidney physiology and pathology. Previous studies suggest that the splice isoform VEGF-A165b (resulting from alternative usage...

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Bibliographic Details
Main Authors: Stevens, Megan, Neal, Christopher R., Salmon, Andrew H.J., Bates, David O., Harper, Steve J., Oltean, Sebastian
Format: Article
Published: Wiley 2017
Subjects:
Vascular endothelial growth factor
alternative splicing
reno-protection
Online Access:https://eprints.nottingham.ac.uk/43073/

Internet

https://eprints.nottingham.ac.uk/43073/

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