RECQL4 helicase has oncogenic potential in sporadic breast cancers

RECQL4 helicase has oncogenic potential in sporadic breast cancers

RECQL4 helicase is a molecular motor that unwinds DNA, a process essential during DNA replication and DNA repair. Germ-line mutations in RECQL4 cause type II Rothmund–Thomson syndrome (RTS), characterized by a premature ageing phenotype and cancer predisposition. RECQL4 is widely considered to be a...

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Main Authors: Arora, Arvind, Agarwal, Devika, Abdel-Fatah, Tarek M.A., Lu, Huiming, Croteau, Deborah L., Moseley, Paul, Aleskandarany, Mohammed A., Green, Andrew R., Ball, Graham, Rakha, Emad A., Chan, Stephen Y.T., Ellis, Ian O., Wang, Lisa L., Zhao, Yongliang, Balajee, Adayabalam S., Bohr, Vilhelm A., Madhusudan, Srinivasan
Format: Article
Published: Wiley 2016
Subjects:
RECQL4 helicase; breast cancer; tumour suppressor; oncogene
Online Access:https://eprints.nottingham.ac.uk/43062/

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