Directed differentiation of human induced pluripotent stem cells into functional cholangiocyte-like cells

The difficulty in isolating and propagating functional primary cholangiocytes is a major limitation in the study of biliary disorders and the testing of novel therapeutic agents. To overcome this problem, we have developed a platform for the differentiation of human pluripotent stem cells (hPSCs) in...

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Bibliographic Details
Main Authors: Sampaziotis, Fotios, de Brito, Miguel Cardoso, Geti, Imbisaat, Bertero, Alessandro, Hannan, Nicholas R.F., Vallier, Ludovic
Format: Article
Published: Nature Publishing Group 2017
Subjects:
Online Access:https://eprints.nottingham.ac.uk/43033/