The mutant p53-ID4 complex controls VEGFA isoforms by recruiting lncRNA MALAT1

The mutant p53-ID4 complex controls VEGFA isoforms by recruiting lncRNA MALAT1

The abundant, nuclear-retained, metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) has been associated with a poorly differentiated and aggressive phenotype of mammary carcinomas. This long non-coding RNA (lncRNA) localizes to nuclear speckles, where it interacts with a subset of spl...

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Bibliographic Details
Main Authors: Pruszko, Magdalena, Milano, Elisa, Forcato, Mattia, Donzelli, S., Ganci, Federica, Di Agostino, Silvia, De Panfilis, Simone, Fazi, Francesco, Bates, David O., Bicciato, Silvio, Zylicz, Maciej, Żylicz, Alicja, Blandino, Giovanni, Fontemaggi, Giulia
Format: Article
Published: Nature Publishing Group 2017
Subjects:
lncRNA
MALAT1
ASF/SF2
SRSF1
ID4
mutant p53
VEGFAxxxb
VEGFA
Online Access:https://eprints.nottingham.ac.uk/43030/

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