Screening for novel endogenous inflammatory stimuli using the secreted embryonic alkaline phosphatase NF-κB reporter assay
An immune response can be activated by pathogenic stimuli, as well as endogenous danger signals, triggering the activation of pattern recognition receptors and initiating signalling cascades that lead to inflammation. This method uses THP1-Blue™ cells, a human monocytic cell line which contains an e...
| Main Authors: | , , |
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| Format: | Article |
| Published: |
Bio-protocol LLC
2017
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| Subjects: | |
| Online Access: | https://eprints.nottingham.ac.uk/42882/ |