Hoxa9 collaborates with E2A-PBX1 in mouse B cell leukemia in association with Flt3 activation and decrease of B cell gene expression

Hoxa9 collaborates with E2A-PBX1 in mouse B cell leukemia in association with Flt3 activation and decrease of B cell gene expression

Background: The fusion protein E2A-PBX1 induces pediatric B cell leukemia in human. Previously, we reported oncogenic interactions between homeobox (Hox) genes and E2A-PBX1 in murine T cell leukemia. A proviral insertional mutagenesis screen with our E2A-PBX1 B cell leukemia mouse model identified H...

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Bibliographic Details
Main Authors: Hassawi, Mona, Shestakova, Elena A., Fournier, Marilaine, Lebert-Ghali, Charles-Étienne, Vaisson, Gratianne, Frison, Héloïse, Sinnett, Daniel, Vidal, Ramon, Thompson, Alexander, Bijl, Janet J.
Format: Article
Published: Wiley 2014
Subjects:
Hox genes; oncogenes; transgenic mouse model; transcription factors
Online Access:https://eprints.nottingham.ac.uk/42822/

Internet

https://eprints.nottingham.ac.uk/42822/

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