Versatile C(sp2)−C(sp3) ligand couplings of sulfoxides for the enantioselective synthesis of diarylalkanes
The reaction of chiral (hetero)aryl benzyl sulfoxides with Grignard reagents affords enantiomerically pure diarylalkanes in up to 98% yield and greater than 99.5% enantiomeric excess. This ligand coupling reaction is tolerant to multiple substitution patterns and provides access to diverse areas of...
| Main Authors: | , , , , |
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| Format: | Article |
| Published: |
Wiley-VCH Verlag
2016
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| Subjects: | |
| Online Access: | https://eprints.nottingham.ac.uk/42752/ |