Hierarchical Bayesian inference for ion channel screening dose-response data

Dose-response (or 'concentration-effect') relationships commonly occur in biological and pharmacological systems and are well characterised by Hill curves. These curves are described by an equation with two parameters: the inhibitory concentration 50% (IC50); and the Hill coefficient. Typi...

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Bibliographic Details
Main Authors: Johnstone, Ross H., Bardenet, Rémi, Gavaghan, David J., Mirams, Gary R.
Format: Article
Published: F1000Research 2017
Online Access:https://eprints.nottingham.ac.uk/42656/