Engineered human pluripotent stem cell derived cardiomyocyte platforms to detect cardiovascular safety liabilities

The development and screening of new chemical entities is often a lengthy and costly process, which relies heavily on the use of animal models for measuring pre-clinical drug safety liabilities. It has been estimated that it now costs pharmaceutical companies in excess of $1 billion and takes typica...

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Bibliographic Details
Main Author: Firth, Karl
Format: Thesis (University of Nottingham only)
Language:English
Published: 2017
Subjects:
Online Access:https://eprints.nottingham.ac.uk/42062/