Crystal structure of signal regulatory protein gamma (SIRPγ) in complex with an antibody Fab fragment

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Crystal structure of signal regulatory protein gamma (SIRPγ) in complex with an antibody Fab fragment

BACKGROUND Signal Regulatory Protein γ (SIRPγ) is a member of a closely related family of three cell surface receptors implicated in modulating immune/inflammatory responses. SIRPγ is expressed on T lymphocytes where it appears to be involved in the integrin-independent adhesion of lymphocytes to...

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Bibliographic Details
Main Authors:	Nettleship, Joanne E., Ren, Jingshan, Scott, David J., Rahman, Nahid, Hatherley, Deborah, Zhao, Yuguang, Stuart, David I., Barclay, A. Neil, Owens, Raymond J.
Format:	Article
Published:	BioMed Central 2013
Subjects:	Antigen-binding complex Signal regulatory protein Receptor structure
Online Access:	https://eprints.nottingham.ac.uk/41975/

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