Crystal structure of signal regulatory protein gamma (SIRPγ) in complex with an antibody Fab fragment

BACKGROUND Signal Regulatory Protein γ (SIRPγ) is a member of a closely related family of three cell surface receptors implicated in modulating immune/inflammatory responses. SIRPγ is expressed on T lymphocytes where it appears to be involved in the integrin-independent adhesion of lymphocytes to...

Full description

Bibliographic Details
Main Authors: Nettleship, Joanne E., Ren, Jingshan, Scott, David J., Rahman, Nahid, Hatherley, Deborah, Zhao, Yuguang, Stuart, David I., Barclay, A. Neil, Owens, Raymond J.
Format: Article
Published: BioMed Central 2013
Subjects:
Online Access:https://eprints.nottingham.ac.uk/41975/