Synthesis of α-glucan in mycobacteria involves a hetero-octameric complex of trehalose synthase TreS and Maltokinase Pep2

Recent evidence established that the cell envelope of Mycobacterium tuberculosis, the bacillus causing tuberculosis (TB), is coated by an α-glucan-containing capsule that has been implicated in persistence in a mouse infection model. As one of three known metabolic routes to α-glucan in mycobacteria...

Full description

Bibliographic Details
Main Authors: Roy, Rana, Usha, Veeraraghavan, Kermani, Ali, Scott, David J., Hyde, Eva I., Besra, Gurdyal S., Alderwick, Luke J., Fütterer, Klaus
Format: Article
Published: American Chemical Society 2013
Online Access:https://eprints.nottingham.ac.uk/41974/