Structure and catalytic regulatory function of ubiquitin specific protease 11 N-terminal and ubiquitin-like domains
The ubiquitin specific protease 11 (USP11) is implicated in DNA repair, viral RNA replication, and TGFβ signaling. We report the first characterization of the USP11 domain architecture and its role in regulating the enzymatic activity. USP11 consists of an N-terminal "domain present in USPs&quo...
| Main Authors: | Harper, Stephen, Gratton, Hayley E., Cornaciu, Irina, Oberer, Monika, Scott, David J., Emsley, Jonas, Dreveny, Ingrid |
|---|---|
| Format: | Article |
| Published: |
American Chemical Society
2014
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| Online Access: | https://eprints.nottingham.ac.uk/41972/ |
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