Structure and catalytic regulatory function of ubiquitin specific protease 11 N-terminal and ubiquitin-like domains

The ubiquitin specific protease 11 (USP11) is implicated in DNA repair, viral RNA replication, and TGFβ signaling. We report the first characterization of the USP11 domain architecture and its role in regulating the enzymatic activity. USP11 consists of an N-terminal "domain present in USPs&quo...

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Bibliographic Details
Main Authors: Harper, Stephen, Gratton, Hayley E., Cornaciu, Irina, Oberer, Monika, Scott, David J., Emsley, Jonas, Dreveny, Ingrid
Format: Article
Published: American Chemical Society 2014
Online Access:https://eprints.nottingham.ac.uk/41972/