Engineering a reagentless biosensor for single-stranded DNA to measure real-time helicase activity in Bacillus

Single-stranded DNA-binding protein (SSB) is a well characterized ubiquitous and essential bacterial protein involved in almost all aspects of DNA metabolism. Using the Bacillus subtilis SSB we have generated a reagentless SSB biosensor that can be used as a helicase probe in B. subtilis and closely...

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Bibliographic Details
Main Authors: Green, Matthew, Gilhooly, Neville S., Abedeen, Shahriar, Scott, David J., Dillingham, Mark S., Soultanas, Panos
Format: Article
Language:English
Published: Elsevier 2014
Subjects:
Online Access:https://eprints.nottingham.ac.uk/41969/