Comparison of the structure and activity of
glycosylated and asglycosylated human carboxylesterase 1

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Comparison of the structure and activity of glycosylated and asglycosylated human carboxylesterase 1

Human Carboxylesterase 1 (hCES1) is the key liver microsomal enzyme responsible for detoxification and metabolism of a variety of clinical drugs. To analyse the role of the single N-linked glycan on the structure and activity of the enzyme, authentically glycosylated and aglycosylated hCES1, generat...

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Bibliographic Details
Main Authors:	Arena de Souza, Victoria, Scott, David J., Nettleship, Joanne E., Rahman, Nahid, Charlton, Michael H., Walsh, Martin A., Owens, Raymond J.
Format:	Article
Published:	Public Library of Science 2015
Online Access:	https://eprints.nottingham.ac.uk/41961/

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