Comparison of the structure and activity of glycosylated and asglycosylated human carboxylesterase 1
Human Carboxylesterase 1 (hCES1) is the key liver microsomal enzyme responsible for detoxification and metabolism of a variety of clinical drugs. To analyse the role of the single N-linked glycan on the structure and activity of the enzyme, authentically glycosylated and aglycosylated hCES1, generat...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Published: |
Public Library of Science
2015
|
| Online Access: | https://eprints.nottingham.ac.uk/41961/ |