STAT2 is a pervasive cytokine regulator due to its inhibition of STAT1 in multiple signaling pathways
STAT2 is the quintessential transcription factor for type 1 interferons (IFNs), where it functions as a heterodimer with STAT1. However, the human and murine STAT2-deficient phenotypes suggest important additional and currently unidentified type 1 IFN-independent activities. Here, we show that STAT2...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Published: |
Public Library of Science
2016
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| Online Access: | https://eprints.nottingham.ac.uk/41956/ |