Scaffold development to engineer human intestinal epithelial tissue grafts

Epithelial crypts isolated from normal colon mucosa have been cultured in vitro in the form of organoids. These organoids have been shown to have regenerative potential when implanted in mouse models of denuded colon mucosa. However, a major limitation in the translation of these studies to a clinic...

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Bibliographic Details
Main Author: Chandaria, Rehma
Format: Thesis (University of Nottingham only)
Language:English
Published: 2017
Online Access:https://eprints.nottingham.ac.uk/41875/