Stress-induced dynamic regulation of mitochondrial STAT3 and its association with cyclophilin D reduces mitochondrial ROS production

Signal Transducer and Activator of Transcription 3 (STAT3) has been tied to various physiological and pathological functions, mainly as a transcription factor that translocates to the nucleus upon tyrosine phosphorylation induced by cytokine stimulation. In addition, a small pool of STAT3 resides in...

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Bibliographic Details
Main Authors: Meier, Jeremy A., Hyun, Moonjung, Cantwell, Marc, Raza, Ali, Mertens, Claudia, Raje, Vidisha, Sisler, Jennifer, Tracy, Erin, Torres-Odio, Sylvia, Gispert, Suzana, Shaw, Peter E., Baumann, Heinz, Bandyopadhyay, Dipankar, Takabe, Kazuaki, Larner, Andrew C.
Format: Article
Published: American Association for the Advancement of Science 2017
Online Access:https://eprints.nottingham.ac.uk/41774/