ZYZ-168 alleviates cardiac fibrosis after myocardial infarction through inhibition of ERK1/2-dependent ROCK1 activation
Selective treatments for myocardial infarction (MI) induced cardiac fibrosis are lacking. In this study, we focus on the therapeutic potential of a synthetic cardio-protective agent named ZYZ-168 towards MI-induced cardiac fibrosis and try to reveal the underlying mechanism. ZYZ-168 was administered...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Published: |
Nature Publishing Group
2017
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| Online Access: | https://eprints.nottingham.ac.uk/41763/ |