Activation of 2′ 5′-oligoadenylate synthetase by stem loops at the 5′-end of the West Nile virus genome

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Activation of 2′ 5′-oligoadenylate synthetase by stem loops at the 5′-end of the West Nile virus genome

West Nile virus (WNV) has a positive sense RNA genome with conserved structural elements in the 5′ and 3′ -untranslated regions required for polyprotein production. Antiviral immunity to WNV is partially mediated through the production of a cluster of proteins known as the interferon stimulated gene...

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Bibliographic Details
Main Authors:	Deo, Soumya, Patel, Trushar R., Dzananovic, Edis, Booy, Evan P., Zeid, Khalid, McEleney, Kevin, Harding, Stephen E., McKenna, Sean A.
Format:	Article
Published:	Public Library of Science 2014
Online Access:	https://eprints.nottingham.ac.uk/41747/

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