Activation of 2′ 5′-oligoadenylate synthetase by stem loops at the 5′-end of the West Nile virus genome
West Nile virus (WNV) has a positive sense RNA genome with conserved structural elements in the 5′ and 3′ -untranslated regions required for polyprotein production. Antiviral immunity to WNV is partially mediated through the production of a cluster of proteins known as the interferon stimulated gene...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Published: |
Public Library of Science
2014
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| Online Access: | https://eprints.nottingham.ac.uk/41747/ |