Location dependent coordination chemistry and MRI relaxivity, in de novo designed lanthanide coiled coils

Location dependent coordination chemistry and MRI relaxivity, in de novo designed lanthanide coiled coils

Herein, we establish for the first time the design principles for lanthanide coordination within coiled coils, and the important consequences of binding site translation. By interrogating design requirements and by systematically translating binding site residues, one can influence coiled coil stabi...

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Bibliographic Details
Main Authors: Berwick, Matthew R., Slope, Louise N., Smith, Caitlin F., King, Siobhan M., Newton, Sarah L., Gillis, Richard B., Adams, Gary G., Rowe, Arthur J., Harding, Stephen E., Britton, Melanie M., Peacock, Anna F. A.
Format: Article
Published: Royal Society of Chemistry 2015
Online Access:https://eprints.nottingham.ac.uk/41718/

Internet

https://eprints.nottingham.ac.uk/41718/

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