Minocycline hepatotoxicity: clinical characterization and identification of HLA-B∗ 35:02 as a risk factor

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Minocycline hepatotoxicity: clinical characterization and identification of HLA-B∗ 35:02 as a risk factor

Minocycline hepatotoxicity can present with prominent autoimmune features in previously healthy individuals. The aim of this study was to identify genetic determinants of minocycline DILI in a well-phenotyped cohort of patients. Methods: Caucasian patients with minocycline DILI underwent genome-wide...

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Bibliographic Details
Main Authors:	Urban, Thomas Jacob, Nicoletti, Paola, Chalasani, Naga, Serrano, Jose, Stolz, Andrew, Daly, Ann K., Aithal, Guruprasad P., Dillon, John F., Navarro, Victor, Odin, Joseph, Barnhart, Huiman X., Ostrov, David, Long, Nanye, Cirulli, Elizabeth Theresa, Watkins, Paul Brent, Fontana, Robert John
Format:	Article
Published:	Elsevier 2017
Subjects:	Drug induced liver injury Single nucleotide polymorphism Genetic association Autoimmunity Human leukocyte antigen
Online Access:	https://eprints.nottingham.ac.uk/41683/

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