Hyperactive mariner transposons are created by mutations that disrupt allosterism and increase the rate of transposon end synapsis

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Hyperactive mariner transposons are created by mutations that disrupt allosterism and increase the rate of transposon end synapsis

New applications for transposons in vertebrate genetics have spurred efforts to develop hyperactive variants. Typically, a genetic screen is used to identify several hyperactive point mutations, which are then incorporated in a single transposase gene. However, the mechanisms responsible for the inc...

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Bibliographic Details
Main Authors:	Liu, Danxu, Chalmers, Ronald
Format:	Article
Published:	Oxford University Press 2014
Online Access:	https://eprints.nottingham.ac.uk/41470/

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