Hyperactive mariner transposons are created by mutations that disrupt allosterism and increase the rate of transposon end synapsis
New applications for transposons in vertebrate genetics have spurred efforts to develop hyperactive variants. Typically, a genetic screen is used to identify several hyperactive point mutations, which are then incorporated in a single transposase gene. However, the mechanisms responsible for the inc...
| Main Authors: | , |
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| Format: | Article |
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Oxford University Press
2014
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| Online Access: | https://eprints.nottingham.ac.uk/41470/ |