Endogenous lysophosphatidic acid (LPA1) receptor agonists demonstrate ligand bias between calcium and ERK signalling pathways in human lung fibroblasts

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Endogenous lysophosphatidic acid (LPA1) receptor agonists demonstrate ligand bias between calcium and ERK signalling pathways in human lung fibroblasts

Background and Purpose Human lung fibroblasts (HLF) express high levels of the LPA1 receptor, a GPCR that responds to the endogenous lipid mediator, lysophosphatidic acid (LPA). Several molecular species or analogues of LPA exist and have been detected in biological fluids such as serum and plasm...

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Bibliographic Details
Main Authors:	Sattikar, Afrah, Dowling, Mark R, Rosethorne, Elizabeth M.
Format:	Article
Published:	Wiley 2017
Online Access:	https://eprints.nottingham.ac.uk/41457/

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