Long receptor residence time of C26 contributes to super agonist activity at the human β2 adrenoceptor
Super agonists produce greater functional responses than endogenous agonists in the same assay, and their unique pharmacology is the subject of increasing interest and debate. We propose that receptor residence time and the duration of receptor signaling contribute to the pharmacology of super agoni...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Published: |
American Society for Pharmacology and Experimental Therapeutics (ASPET)
2016
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| Online Access: | https://eprints.nottingham.ac.uk/41456/ |