Identification of a Cyanine-dye labeled peptidic ligand for Y₁R and Y₄R, based upon the Neuropeptide Y C-terminal analogue, BVD-15

Identification of a Cyanine-dye labeled peptidic ligand for Y₁R and Y₄R, based upon the Neuropeptide Y C-terminal analogue, BVD-15

Traceable truncated Neuropeptide Y (NPY) analogues with Y₁ receptor (Y₁R) affinity and selectivity are highly desirable tools in studying receptor location, regulation, and biological functions. A range of fluorescently labeled analogues of a reported Y₁R/Y₄R preferring ligand BVD-15 have been prepa...

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Bibliographic Details
Main Authors: Liu, Mengjie, Richardson, Rachel R., Mountford, Simon J., Zhang, Lei, Tempone, Matheus H., Herzog, Herbert, Holliday, Nicholas D., Thompson, Philip E.
Format: Article
Published: American Chemical Society 2016
Subjects:
Neuropeptide Y
Fluorescent ligand
G protein coupled receptor
High content imaging
Online Access:https://eprints.nottingham.ac.uk/41450/

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https://eprints.nottingham.ac.uk/41450/

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