Cryptorchidism in the orl rat is associated with muscle patterning defects in the fetal gubernaculum and altered hormonal signaling

Cryptorchidism, or undescended testis, is a common male genital anomaly of unclear etiology. Hormonal stimulation of the developing fetal gubernaculum by testicular androgens and insulin-like 3 (INSL3) is required for testicular descent. In studies of the orl fetal rat, one of several reported strai...

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Main Authors: Barthold, Julia S., Robbins, Alan, Wang, Yanping, Pugarelli, Joan, Mateson, Abigail, Anand-Ivell, Ravinder, Ivell, Richard, McCahan, Suzanne M., Akins, Robert E., Jr.
Format: Article
Published: Society for the Study of Reproduction 2014
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Online Access:https://eprints.nottingham.ac.uk/41429/