Continuous N-alkylation reactions of amino alcohols using γ-Al2O3 and supercritical CO2: unexpected formation of cyclic ureas and urethanes by reaction with CO2
The use of γ-Al2O3 as a heterogeneous catalyst in scCO2, has be successfully applied to the amination of alcohols for the synthesis of N-alkylated heterocycles. The optimal reaction conditions (temperature and substrate flow rate) were determined using an automated self-optimising reactor, resulting...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Published: |
Beilstein-Institut
2017
|
| Subjects: | |
| Online Access: | https://eprints.nottingham.ac.uk/41185/ |