Jerantinine A induces tumor-specific cell death through modulation of splicing factor 3b subunit 1 (SF3B1)
Precursor mRNA (pre-mRNA) splicing is catalyzed by a large ribonucleoprotein complex known as the spliceosome. Numerous studies have indicated that aberrant splicing patterns or mutations in spliceosome components, including the splicing factor 3b subunit 1 (SF3B1), are associated with hallmark canc...
| Main Authors: | , , , , , , , , , , , , , , |
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| Format: | Article |
| Published: |
Nature Publishing Group
2017
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| Online Access: | https://eprints.nottingham.ac.uk/41150/ |