Alkylation of staurosporine to derive a kinase probe for fluorescence applications
The natural product staurosporine is a high-affinity inhibitor of nearly all mammalian protein kinases.The labelling of staurosporine has proven effective as a means of generating protein kinase research tools. Most tools have been generated by acylation of the 4’-methylamine of the sugar moiety of...
| Main Authors: | , , |
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| Format: | Article |
| Published: |
Wiley-VCH Verlag
2016
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| Online Access: | https://eprints.nottingham.ac.uk/40837/ |