Pharmacological analysis and structure determination of
7-methylcyanopindolol–bound b1-adrenergic receptor

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Pharmacological analysis and structure determination of 7-methylcyanopindolol–bound b1-adrenergic receptor

Comparisons between structures of the b1-adrenergic receptor (AR) bound to either agonists, partial agonists, or weak partial agonists led to the proposal that rotamer changes of Ser5.46, coupled to a contraction of the binding pocket, are sufficient to increase the probability of receptor activatio...

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Bibliographic Details
Main Authors:	Sato, Tomomi, Baker, Jillian G., Warne, Tony, Brown, Giles A., Leslie, Andrew, Congreve, Miles, Tate, Christopher G.
Format:	Article
Published:	ASPET 2015
Online Access:	https://eprints.nottingham.ac.uk/40727/

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