A clinical evaluation of the pharmacokinetics and pharmacodynamics of intravenous alfaxalone in cyclodextrin in male and female rats following a loading dose and constant rate infusion
Objective: To characterise, as a clinical study, the pharmacokinetics and pharmacodynamics and describe the hypnotic effect of the neurosteroid alfaxalone (3α-hydroxy-5 α-pregnane-11, 20-dione) formulated with 2-hydroxypropyl-β-cyclodextrin in male and female rats. Study design: Prospective, experi...
| Main Authors: | , , |
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| Format: | Article |
| Published: |
Wiley
2017
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| Online Access: | https://eprints.nottingham.ac.uk/40482/ |