Elevated 5hmC levels characterize DNA of the cerebellum in Parkinson’s disease

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Elevated 5hmC levels characterize DNA of the cerebellum in Parkinson’s disease

5-methylcytosine and the oxidation product 5-hydroxymethylcytosine are two prominent epigenetic variants of the cytosine base in nuclear DNA of mammalian brains. We measured levels of 5-methylcytosine and 5-hydroxymethylcytosine by enzyme-linked immunosorbent assay in DNA from post-mortem cerebella...

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Bibliographic Details
Main Authors:	Stöger, Reinhard, Scaife, Paula, Shephard, Freya, Chakrabarti, Lisa
Format:	Article
Published:	Nature Publishing Group 2017
Subjects:	DNA epigenetics Parkinson's disease
Online Access:	https://eprints.nottingham.ac.uk/40271/

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