Elevated 5hmC levels characterize DNA of the cerebellum in Parkinson’s disease
5-methylcytosine and the oxidation product 5-hydroxymethylcytosine are two prominent epigenetic variants of the cytosine base in nuclear DNA of mammalian brains. We measured levels of 5-methylcytosine and 5-hydroxymethylcytosine by enzyme-linked immunosorbent assay in DNA from post-mortem cerebella...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Published: |
Nature Publishing Group
2017
|
| Subjects: | |
| Online Access: | https://eprints.nottingham.ac.uk/40271/ |