Evolution of complexity in the zebrafish synapse proteome

The proteome of human brain synapses is highly complex and mutated in over 130 diseases. This complexity arose from two whole genome duplications early in the vertebrate lineage. Zebrafish are used in modelling human diseases, however its synapse proteome is uncharacterised and whether the teleost-s...

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Bibliographic Details
Main Authors: Bayes, Alex, Collins, Mark O., Reig-Vader, Rrita, Gou, Gemma, Goulding, David, Izquierdo, Abril, Choudhary, Jyoti S., Emes, Richard D., Grant, Seth G.N.
Format: Article
Published: Nature Publishing Group 2017
Online Access:https://eprints.nottingham.ac.uk/40100/