MMP-1 activation contributes to airway smooth muscle growth and asthma severity

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MMP-1 activation contributes to airway smooth muscle growth and asthma severity

Introduction: Matrix metalloproteinase-1 and mast cells are present in the airways of people with asthma. We hypothesised that matrix metalloproteinase-1 could be activated by mast cells and increase asthma severity. Methods: Patients with stable asthma and healthy controls underwent spirometry, met...

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Bibliographic Details
Main Authors:	Naveed, Shams-un-nisa, Clements, Debbie, Jackson, David J., Philp, Christopher, Billington, Charlotte K., Soomro, Irshad N., Reynolds, Catherine, Harrison, Timothy W., Johnston, Sebastian L., Shaw, Dominick E., Johnson, Simon R.
Format:	Article
Published:	American Thoracic Society 2017
Subjects:	Asthma Extracellular matrix Airway remodeling Airway smooth muscle Mast cells
Online Access:	https://eprints.nottingham.ac.uk/40029/

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