MMP-1 activation contributes to airway smooth muscle growth and asthma severity

MMP-1 activation contributes to airway smooth muscle growth and asthma severity

Introduction: Matrix metalloproteinase-1 and mast cells are present in the airways of people with asthma. We hypothesised that matrix metalloproteinase-1 could be activated by mast cells and increase asthma severity. Methods: Patients with stable asthma and healthy controls underwent spirometry, met...

Full description

Bibliographic Details
Main Authors: Naveed, Shams-un-nisa, Clements, Debbie, Jackson, David J., Philp, Christopher, Billington, Charlotte K., Soomro, Irshad N., Reynolds, Catherine, Harrison, Timothy W., Johnston, Sebastian L., Shaw, Dominick E., Johnson, Simon R.
Format: Article
Published: American Thoracic Society 2017
Subjects:
Asthma
Extracellular matrix
Airway remodeling
Airway smooth muscle
Mast cells
Online Access:https://eprints.nottingham.ac.uk/40029/

Internet

https://eprints.nottingham.ac.uk/40029/

Similar Items