Characterisation of a monoclonal antibody raised against a thermostabilised β1-adrenoceptor

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Characterisation of a monoclonal antibody raised against a thermostabilised β1-adrenoceptor

The β1-adrenoceptor (β1-AR) is an important regulator of cardiac function. Chronic stimulation and subsequent downregulation of cardiac β1-ARs have been implicated in heart failure. Recently, it has been demonstrated that antibodies which target the second extracellular loop (ECL2) of the human β1...

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Bibliographic Details
Main Author:	Soave, Mark
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2017
Online Access:	https://eprints.nottingham.ac.uk/39890/

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