Characterisation of a monoclonal antibody raised against a thermostabilised β1-adrenoceptor
The β1-adrenoceptor (β1-AR) is an important regulator of cardiac function. Chronic stimulation and subsequent downregulation of cardiac β1-ARs have been implicated in heart failure. Recently, it has been demonstrated that antibodies which target the second extracellular loop (ECL2) of the human β1...
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| Format: | Thesis (University of Nottingham only) |
| Language: | English |
| Published: |
2017
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| Online Access: | https://eprints.nottingham.ac.uk/39890/ |